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Cannabis Pharmacokinetics

Presented by Associate Professor Ali Seyfoddin.

About this module:

In this presentation, pharmacology expert Associate Professor Ali Seyfoddin (New Zealand) takes us through the pharmacokinetics of medicinal cannabis, covering the routes of delivery of cannabis (inhalation, oral, buccal, rectal and transdermal routes) and the associated absorption characteristics, distribution, metabolism and elimination. THC bioavailability, time for maximum plasma concentrations, and potential for drug-cannabinoid interactions is also examined.

This presentation is suitable for healthcare practitioners and those with a background in biomedical sciences. It assumes a knowledge of the endocannabinoid system and medicinal cannabis pharmacodynamics.
Learning Outcomes

At the end of this module, learners will be able to:

  • Debate the advantages and disadvantages of various routes of delivery of medicinal cannabis.
  • Compare the bioavailability of THC for various routes of delivery of medicinal cannabis and discuss factors that can impact on bioavailability. 
  • Describe the distribution of THC within the body.
  • Describe the metabolism and elimination of THC in the body.
  • Explain why CBD and THC may interact with certain medications. 
MEET THE INSTRUCTOR

Assoc Prof. Ali Seyfoddin

Dr Ali Seyfoddin is the Deputy Head of School of Science at Auckland University of Technology. Trained as a pharmacist, he leads the Drug Delivery Research Group (www.drugdelivery.aut.ac.nz) and his research interests are primarily pharmaceutical formulation, biological engineering and bioprospecting.

Being practically minded, he finds application for his research in natural drug discovery, nanoencapsulation, 3D- and bio-printing, aquaculture feed technology and medicinal cannabis (cultivation, processing, extraction and formulation). He also teaches a range of undergraduate and postgraduate courses related to pharmacology, biomedical sciences and medicinal cannabis science.
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